Role of Non Receptor Tyrosine Kinases in ... | 水果好營養
由KSSiveen著作·2018·被引用90次—Non-receptortyrosinekinases(NRTK)areasub-groupoftyrosinekinases,whichcanrelayintracellularsignalsoriginatingfromextracellular ...
Tyrosine kinases belong to a family of enzymes that mediate the movement of the phosphate group to tyrosine residues of target protein, thus transmitting signals from the cell surface to cytoplasmic proteins and the nucleus to regulate physiological processes. Non-receptor tyrosine kinases (NRTK) are a sub-group of tyrosine kinases, which can relay intracellular signals originating from extracellular receptor. NRTKs can regulate a huge array of cellular functions such as cell survival, division/propagation and adhesion, gene expression, immune response, etc. NRTKs exhibit considerable variability in their structural make up, having a shared kinase domain and commonly possessing many other domains such as SH2, SH3 which are protein-protein interacting domains. Recent studies show that NRTKs are mutated in several hematological malignancies, including lymphomas, leukemias and myelomas, leading to aberrant activation. ...
Non | 水果好營養
Role of Non Receptor Tyrosine Kinases in Hematological ... | 水果好營養
Role of Non Receptor Tyrosine Kinases in ... | 水果好營養
Non | 水果好營養
Non | 水果好營養
Non-Receptor Tyrosine Kinase (PTKS) | 水果好營養
Non | 水果好營養
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