Saturated and unsaturated (including arachidonic acid) non ... | 水果好營養
![Saturated and unsaturated (including arachidonic acid) non ...](https://i.imgur.com/Dp6k9gg.jpg)
由DKeane著作·2008·被引用53次—Saturatedandunsaturated(includingarachidonicacid)non-esterifiedfattyacidmodulationofinsulinsecretionfrompancreaticbeta-cells·Authors.
![Saturated and unsaturated (including arachidonic acid) non ...](https://i.imgur.com/Dp6k9gg.jpg)
Both stimulatory and detrimental effects of NEFAs (non-esterified fatty acids) on pancreatic beta-cells have been recognized. Acute exposure of the pancreatic beta-cell to high glucose concentrations and/or saturated NEFAs results in a substantial increase in insulin release, whereas chronic exposure results in desensitization and suppression of secretion followed by induction of apoptosis. Some unsaturated NEFAs also promote insulin release acutely, but they are less toxic to beta-cells during chronic exposure and can even exert positive protective effects. In the present review, we focus on exogenous and endogenous effects of NEFAs, including the polyunsaturated fatty acid, arachidonic acid (or its metabolites generated from cyclo-oxygenase activity), on beta-cell metabolism, and have explored the outcomes with respect to beta-cell insulin secretion.
Arachidonic acid and other unsaturated fatty acids and some ... | 水果好營養
Arachidonic acid | 水果好營養
Arachidonic acid is an unsaturated fatty acid | 水果好營養
Arachidonic acid | 水果好營養
Arachidonic acid | 水果好營養
Arachidonic Acid | 水果好營養
Saturated and unsaturated (including arachidonic acid) non ... | 水果好營養
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