8.5 | 水果好營養
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2021年3月5日—Asthenamesuggests,areceptortyrosinekinaseisacellsurfacereceptorthatalsohasatyrosinekinaseactivity.Thesignalbindingdomain ...
![8.5](https://i.imgur.com/Dp6k9gg.jpg)
Receptor tyrosine kinases mediate responses to a large number of signals, including peptide hormones like insulin and growth factors like epidermal growth factor. Like the GPCRs, receptor tyrosine kinases bind a signal, then pass the message on through a series of intracellular molecules, the last of which acts on target proteins to change the state of the cell.
Figure 8.5.1: Receptor Tyrosine Kinase before signal bindingAs the name suggests, a receptor tyrosine kinase is a cell surface receptor that also has a tyrosine kinase activity. The signal binding domain of the receptor tyrosine kinase is on the cell surface, while the tyrosine kinase enzymatic activity resides in the cytoplasmic part of the protein (see figure above). A transmembrane alpha helix connects these two regions of the receptor.
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8.5 | 水果好營養
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