Tyrosine kinase inhibitors | 水果好營養
![Tyrosine kinase inhibitors](https://i.imgur.com/Dp6k9gg.jpg)
由JTHartmann著作·2009·被引用577次—Tyrosinekinaseinhibitors(TKI)areeffectiveinthetargetedtreatmentofvariousmalignancies.Imatinibwasthefirsttobeintroducedintoclinical ...
![Tyrosine kinase inhibitors](https://i.imgur.com/Dp6k9gg.jpg)
Tyrosine kinase inhibitors (TKI) are effective in the targeted treatment of various malignancies. Imatinib was the first to be introduced into clinical oncology, and it was followed by drugs such as gefitinib, erlotinib, sorafenib, sunitinib, and dasatinib. Although they share the same mechanism of action, namely competitive ATP inhibition at the catalytic binding site of tyrosine kinase, they differ from each other in the spectrum of targeted kinases, their pharmacokinetics as well as substance-specific adverse effects. With variations from drug to drug, tyrosine kinase inhibitors cause skin toxicity, including folliculitis, in more than 50% of patients. Among the tyrosine kinase inhibitors that are commercially available as yet, the agents that target EGFR, erlotinib and gefitinib, display the broadest spectrum of adverse effects on skin and hair, including folliculitis, paronychia, facial hair growth, facial eryt...
Definition of tyrosine kinase inhibitor | 水果好營養
Tyrosine kinase inhibitor | 水果好營養
Tyrosine Kinase Inhibitors | 水果好營養
Tyrosine Kinase Inhibitor (TKI) Therapy | 水果好營養
Tyrosine kinase inhibitors | 水果好營養
Tyrosine kinase inhibitors for solid tumors in the past 20 years ... | 水果好營養
Tyrosine Kinase Inhibitors | 水果好營養
Advances in studies of tyrosine kinase inhibitors and their ... | 水果好營養
Tyrosine Kinase Inhibitors [Antitumor Agents] | 水果好營養
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